The long view
A gut microbiome fix for peanut allergy
Researchers are testing whether transplanting gut microbes from a healthy donor can dial back a peanut allergy, an alternative to the slow, daily dose-escalation of standard oral immunotherapy. The stakes are whether a single day of treatment can meaningfully and durably loosen a food allergy's grip, and a larger placebo-controlled trial in children is already underway to test how far the effect holds.
Latest · Aug 6, 2026 Rima Rachid of Boston Children's Hospital led a trial in which 15 adults with peanut allergies swallowed 36 capsules of donor stool in a single day, and four months later six of them could eat far more peanut without reacting, most tolerating a whole peanut's worth of peanut flour and one tolerating four peanuts.
What’s next: Whether a larger, placebo-controlled trial already underway in children confirms the effect and clarifies why some participants saw no benefit while others did.
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