Life Sciences & Medicine Active Updated Aug 31, 2026

CAR T cell therapy moves from cancer into autoimmune disease

Charité in Berlin ran the world's first trial using CAR T-cell therapy, a technique built to fight cancer, against severe rheumatoid arthritis that had resisted every other treatment. The stakes are whether clearing out the memory B cells suspected of driving chronic autoimmune inflammation can produce durable, medication-free remission at a scale beyond a handful of patients.

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  1. Aug 31, 2026 Latest

    Prof. David Simon's team at Charite in Berlin gave CAR T-cell therapy to six patients with severe, treatment-resistant rheumatoid arthritis, and disease activity dropped in all six, with three no longer needing any rheumatoid arthritis medication by the end of the observation period.

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