Life Sciences & Medicine Active Updated Oct 5, 2026
Gene therapy for inherited blindness
Where it stands as of Oct 5, 2026
A Michigan State University team reported that a single injection of a virus carrying a working CaBP4 gene stopped blindness from progressing in whippets and improved vision, especially in dim light. The treated retinas also expanded the layer that holds the visual connectors, a repair many researchers had thought impossible in adult mammals. The condition is rare and the work is in dogs, so whether it works in people remains untested.
The story so far
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Oct 5, 2026 Latest
A Michigan State University team reported that a single retinal injection of a harmless virus carrying a working CaBP4 gene stopped blindness from progressing in whippets and substantially improved vision, especially in dim light. Treated regions of the retina degraded less, and the outer plexiform layer and the synaptic ribbons inside light-sensing cells expanded.
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