Technology & Innovation Active Updated Aug 14, 2026
A designer enzyme reverses aging's chemical rust
Structural proteins that make up roughly 70 percent of the body accumulate sugar-protein damage called advanced glycation end products over decades, buildup long considered irreversible. A newly designed enzyme reversed that chemical damage in donor tissue, reopening a part of aging biology researchers had largely given up on, with the stakes being whether the effect can move from a dish to a safe therapy in a living body.
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Aug 14, 2026 Latest
Scientists at Revel Pharmaceuticals designed a synthetic enzyme that targets advanced glycation end products, the sugar-protein buildup nicknamed the body's rust, and applied it to tissue from a 75-year-old donor, bringing AGE levels down to what is typically seen in a 30-year-old's tissue.
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