Lifesavers · No. 11
Tuberculosis treatment
Finding and treating tuberculosis has saved an estimated 83 million lives since 2000, turning the disease that has killed more people than any other infection into one a course of antibiotics can cure.
Updated
A WHO estimate of the toll averted by global TB efforts since 2000, restated in the Global Tuberculosis Report 2025.
How it saves lives
Tuberculosis is caused by a slow-growing bacterium that usually settles in the lungs and can sit quietly for years before it turns deadly. The cure is not one drug but a combination of antibiotics taken for months, long enough to kill the bacteria at every stage of their sluggish life cycle. Catching a case early and seeing the treatment through also stops that person from passing the infection to anyone else.
The story
For most of human history tuberculosis, the wasting cough once called consumption, was simply part of the background of death. Robert Koch found the bacterium responsible in 1882, but knowing the cause did not cure anyone. That took until 1943, when Albert Schatz, working in Selman Waksman's lab, pulled the antibiotic streptomycin out of a soil microbe and gave doctors their first drug that actually worked. Combination therapy followed, and over the past quarter century the patient work of finding cases and treating them has saved tens of millions of lives. It is not finished. TB still kills over 1.2 million people a year, drug-resistant strains are harder and costlier to treat, and progress now leans on funding that has stalled.
From the record
Global efforts to combat TB have saved an estimated 83 million lives since the year 2000.
From the record
Tuberculosis is preventable and curable.
From the record
Tuberculosis (TB) remains one of the world's deadliest infectious killers, claiming over 1.2 million lives and affecting an estimated 10.7 million people last year.
Asked often
How many lives has tuberculosis treatment saved?
The World Health Organization estimates that global efforts to find and treat TB have saved about 83 million lives since the year 2000. TB still causes over 1.2 million deaths a year, so the work is far from over.
Is tuberculosis curable?
Yes. The WHO states that tuberculosis is preventable and curable. Standard drug-susceptible TB is treated with a combination of antibiotics taken for months, and treatment success rates are high when patients complete the full course.
Further reading
Read the whole story
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The history
The Remedy (opens Bookshop.org)
Thomas Goetz · 2014
Thomas Goetz follows Robert Koch's 1882 identification of the tubercle bacillus and the failed cure he announced in 1890, as seen by Arthur Conan Doyle.
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The history
The Forgotten Plague (opens Bookshop.org)
Frank Ryan · 1993
Physician Frank Ryan tells the story of the researchers who found streptomycin and the later drugs that cured tuberculosis, and how drug resistance and HIV brought it back.
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