Lifesavers · No. 05

Oral rehydration therapy

A mixture of water, salt and sugar that costs pennies has saved more than 70 million children from dying of dehydration.

70 million lives — children saved from fatal dehydration, 1982 to 2019

An estimate; the true figure cannot be known exactly, but is in the tens of millions.

Credited to
Developed in the 1960s and proven in the field in South Asia; researchers including Dilip Mahalanabis showed it worked in a 1971 refugee-camp cholera outbreak.
When
1960s to 1970s

How it saves lives

Diarrhoea kills by draining the body of water and salts until the organs fail. For a long time the only fix was an intravenous drip, which needs a clinic and staff. The discovery was that adding a little glucose lets the gut absorb water and salt together even during severe illness, so a drink mixed at home can rescue a child a drip once did.

The story

During a cholera outbreak in crowded refugee camps in 1971, with IV fluids running out, doctors tried giving patients a simple sugar-and-salt solution to drink. Death rates fell dramatically. The recipe was almost too simple to believe, which is partly why it took years to spread. Today packets of oral rehydration salts sit in clinics and homes across the world, and The Lancet once called the idea the most important medical advance of the century.

From the record

the number of children saved from 1982 until 2019 by ORT could be more than 70 million

Our World in Data Oral rehydration therapy, 2021

From the record

the most important medical advance of the 20th century

The Lancet quoted by Our World in Data Oral rehydration therapy, 2021

Asked often

How many lives has oral rehydration therapy saved?

Our World in Data estimates that oral rehydration therapy saved more than 70 million children between 1982 and 2019 by treating the dehydration caused by diarrhoea.

What is in oral rehydration solution?

It is a precise mix of clean water, salt and sugar (glucose). The glucose is the key: it lets the gut absorb water and salt together even during severe diarrhoea.

The next one is being invented now.

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