The Ledger · Entry 17
Guinea worm is close to becoming the second disease ever wiped out
Reported human cases of Guinea worm disease worldwide
Guinea worm is a parasite you swallow in unclean water. A year later a metre-long worm burns its way out through the skin, disabling people for weeks, often right at harvest time. There is no drug and no vaccine. The only tools are teaching people to filter their water and keeping the sick from wading back into it.
The key rows
A global campaign led by the WHO and the Carter Center began in the 1980s, and reported cases fell from hundreds of thousands to a handful. Early figures understate the true burden, because surveillance was patchy before the campaign, so the reported peak of 892,055 in 1989 reflects better counting as much as a worse year. The last stretch is the hardest: a few cases still surface, in people and now in dogs, so the disease has not yet been certified as gone.
Asked often
Is Guinea worm disease almost eradicated?
Very nearly. Reported human cases fell from a peak of 892,055 in 1989 to about 10 in 2025. If the last cases can be stopped, Guinea worm would be the second human disease ever eradicated, after smallpox, and the first wiped out without a vaccine or a drug.
How is Guinea worm being eradicated without a vaccine?
Entirely by changing behaviour: filtering drinking water through fine cloth, treating ponds, and keeping infected people and animals out of water sources. Breaking the parasite's life cycle is enough, because it needs a human or animal host to complete it.
Why haven't cases reached zero?
The last cases cluster in a few hard-to-reach and insecure areas, and the parasite has turned up in dogs, which complicates the final push. Until there are no cases for several years, the disease cannot be certified as eradicated.
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