The Ledger · Entry 17

Guinea worm is close to becoming the second disease ever wiped out

Reported human cases of Guinea worm disease worldwide

892,055 in 1989
10 in 2025

Data: Our World in Data, based on WHO and The Carter Center

Guinea worm is a parasite you swallow in unclean water. A year later a metre-long worm burns its way out through the skin, disabling people for weeks, often right at harvest time. There is no drug and no vaccine. The only tools are teaching people to filter their water and keeping the sick from wading back into it.

Reported human cases of Guinea worm disease (dracunculiasis) worldwide, 1980 to 2025: from 35,894 to 10. Source: Our World in Data, based on WHO and The Carter Center. 892,055 1989 75,223 2000 1,797 2010 10 2025
Source: Our World in Data, based on WHO and The Carter Center · CC BY 4.0 · retrieved 2026-07-09. Underlying data: World Health Organization; The Carter Center dracunculiasis eradication programme.

The key rows

1989 892,055 The reported peak, as the campaign's surveillance ramped up.
2000 75,223 Down more than tenfold in a decade.
2010 1,797 Into the low thousands, closing on the last strongholds.
2025 10 Ten reported cases, in a few countries.

A global campaign led by the WHO and the Carter Center began in the 1980s, and reported cases fell from hundreds of thousands to a handful. Early figures understate the true burden, because surveillance was patchy before the campaign, so the reported peak of 892,055 in 1989 reflects better counting as much as a worse year. The last stretch is the hardest: a few cases still surface, in people and now in dogs, so the disease has not yet been certified as gone.

Asked often

Is Guinea worm disease almost eradicated?

Very nearly. Reported human cases fell from a peak of 892,055 in 1989 to about 10 in 2025. If the last cases can be stopped, Guinea worm would be the second human disease ever eradicated, after smallpox, and the first wiped out without a vaccine or a drug.

How is Guinea worm being eradicated without a vaccine?

Entirely by changing behaviour: filtering drinking water through fine cloth, treating ponds, and keeping infected people and animals out of water sources. Breaking the parasite's life cycle is enough, because it needs a human or animal host to complete it.

Why haven't cases reached zero?

The last cases cluster in a few hard-to-reach and insecure areas, and the parasite has turned up in dogs, which complicates the final push. Until there are no cases for several years, the disease cannot be certified as eradicated.

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