Lifesavers · No. 02

Smallpox eradication

Smallpox killed about 300 million people in the 20th century alone, and in 1980 became the first human disease ever deliberately wiped from the Earth.

300 million lives — deaths it caused in the 20th century before eradication in 1980

The figure is the disease's toll in one century; eradication means that toll is now zero.

Credited to
Edward Jenner (1796 vaccine); the global eradication was led by the WHO and epidemiologist Donald Henderson.
When
eradicated 1980

How it saves lives

There is no cure for smallpox, so the campaign worked by finding every outbreak and vaccinating a ring of people around it until the virus had nowhere left to go. Because humans were the only host, cutting off transmission everywhere meant the virus simply ran out of people and vanished.

The story

For at least three thousand years smallpox was one of humanity's great killers, scarring and blinding those it did not kill. In the 20th century alone it took hundreds of millions of lives. A global effort of thousands of health workers, chasing the last cases across deserts and villages, ended it. On 8 May 1980 the World Health Assembly declared the world free of smallpox, the only human disease ever eradicated.

From the record

killing 300 million people in the 20th century alone

World Health Organization Commemorating Smallpox Eradication, 2020

From the record

The world and all its peoples have won freedom from smallpox.

33rd World Health Assembly official declaration, 8 May 1980 Commemorating Smallpox Eradication, 1980

Asked often

How many people did smallpox kill?

The WHO states smallpox killed about 300 million people in the 20th century alone, and it had plagued humanity for at least 3,000 years before that.

When was smallpox eradicated?

The 33rd World Health Assembly declared smallpox eradicated on 8 May 1980. It remains the only human disease ever eradicated.

The next one is being invented now.

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